PAMP immunotherapy

Cancer fever therapy is more than 150 years old. This treatment, without doubt, resulted in many extraordinary healings of late-stage, inoperable cancers "which would be difficult to achieve today" (Mantovani, Nature, 2008).  On the molecular level, remissions were not understood for a long time. Fever therapy fell out of favour with the invention of radiation and chemotherapy. However, cancer mortality remains almost unchanged, we do not seem to come to grips with cancer. So in research attention is turning towards the role of the immune system in cancer again. To reflate the old successes we suggest to implement a modified form of the old fever therapy call PAMP-immunotherapy. 

 (C) Uwe Hobohm