Cancer fever therapy is more than 150 years old. Using injected bacterial extracts, both remarcable remissions as well as failures were achieved at the beginning of the 20th century. On the molecular level, remissions were not understood for a long time. Fever therapy fell out of favour with the invention of radiation and chemotherapy. However, cancer mortality remains almost unchanged, we do not seem to come to grips with cancer. So in research attention is turning towards the role of the immune system in cancer again. To reflate the old successes we suggest to implement a modified form of mistletoe therapy we call augmented mistletoe therapy (AMT).